Symptomatic outcome of pancreatic enzyme replacement therapy in cases of pancreatic exocrine insufficiency
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/02/062996
- Lead Sponsor
- Dr Somya Goel
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Clinically confirmed case of acute and chronic pancreatitis with exocrine insufficiency in patients above 18 years of age
Patients with Baltahazar CT severity index of 2 and more
Exclusion Criteria
Other pancreatic pathology like pancreatic malignancy, cyst.
Contraindicated cases for contrast ct study.
Patients where quality of life cannot be assessed
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Assess reduction in pain, bloating and sticky stool and weight changes post pancreatic enzyme replacement therapy in patients of pancreatic exocrine insufficiency <br/ ><br>Timepoint: 0 days 15 days 45 days
- Secondary Outcome Measures
Name Time Method Grading of complaints of pain on the basis of ‘visual analogue scale’ <br/ ><br>Grading of CT scan findings based on Baltahazar CT severity index <br/ ><br>Documentation of weight changes pre and post therapy using same standard weighing scale . <br/ ><br>General improvement in clinical symptoms and lifestyle changes will be assessed through WHO quality of life scale <br/ ><br>Regular follow up at 0 days – 15 days – 45 days to check compliance towards therapy will be done first hand using Morisky Medication Adherence Scale (MMAS-8) <br/ ><br>Timepoint: 16 MONTHS TO 34 MONTHS