High Intensity Interval Training in Geriatrics
- Conditions
- Muscle WeaknessGait, Unsteady
- Interventions
- Other: Traditionnal group rehabilitationOther: high intensity interval training-HIIT
- Registration Number
- NCT02318459
- Lead Sponsor
- University Hospital, Geneva
- Brief Summary
This is a pilot study for evaluating the feasibility of using High Intensity Interval Training in geriatric hospitalized patients compared to the standard current rehabilitation practice.
- Detailed Description
High Intensity Interval Training (HIIT) has shown a superior effectiveness and efficiency when compared to Moderate Intensity Continuous Training (MICT) in several types of patients and in healthy subjects. There are no data on HIIT in a general geriatric population. This study is a pilot study evaluating the feasibility of using HIIT in geriatric hospitalized patients compared to the standard current rehabilitation practice without HIIT. It is our desire to perform a larger randomized comparative trial between HIIT and MICT if the pilot study proves its feasibility.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 100
- Patients aged 65 years and older hospitalized for rehabilitation after an acute medical condition
- Expected duration of the rehabilitation ≥ 2 weeks
- Ability to follow instructions to perform a Timed up and Go Test
- Ability to perform exercises
- Willing to participate in 4 sessions of HIIT per week for 2 weeks
- Any acute condition with tachycardia, hypotension or fever.
- Abnormal cycle ergometer stress test with
- significant ECG modification
- decrease of more than 20 mmHg of the blood pressure with exercise
- angina
- ST depression at a workload <6 METs
- Inability to reach an intensity of 15/20 in the Borg's scale of perceived exertion
- Any unresolved acute medical or surgical condition of the following kind:
- acute heart failure
- acute coronary syndrome < 1 month
- strole < 1 month
- active pericarditis / myocarditis / endocarditis
- thromboembolic disease with < 2 weeks of anticoagulation
- acute infection requiring intravenous treatment
- ongoing intravenous perfusion
- surgery < 2 months
- recent bone fracture
- Previous episode of primary cardiac arrest (ie, cardiac arrest that did not occur in the presence of an acute myocardial infarction or during a cardiac procedure).
- Severe heart failure (NYHA III and IV)
- Severe stenotic or regurgitant valvular disease
- Uncontrolled hypertension at rest (SBP≥160mmHg, DBP≥100mmHg)
- Uncontrolled dysrhythmia
- Non-sustained ventricular tachycardia with exercise
- Implanted defibrillator
- Obstructive cardiomyopathy
- Resting HR > 100/min
- Severe peripheral artery disease
- Severe COPD (VEMS < 50%)
- Exercise-induced asthma
- Oxygen dependency
- Muscular-skeletal anomaly that may limit exercise participation
- Delirium
- Inability to follow instructions
- Inability to consent
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Traditionnal rehabilitation Traditionnal group rehabilitation Traditionnal group rehabilitation 3 times a week, 1 hour duration. high intensity interval training-HIIT high intensity interval training-HIIT HIIT 4 times a week, 30 minutes duration
- Primary Outcome Measures
Name Time Method Proportion of patients who complete the rehabilitation program 2 weeks
- Secondary Outcome Measures
Name Time Method Distance walked in the 6MWT 2 weeks Muscle strength assessed for the upper and lower extremities 2 weeks upper extremity : handgrip strength using the Baseline Pneumatic Bulb Hand Dynamometer Pinch Gauge; Lower exremity : knee flexion \& extension and ankle flexion \& extension using Microfet2™portable Dynamometer.
Step variability changes as a measure of quality of ambulation 2 weeks Variability measured with GaitRite step analysis system
Trial Locations
- Locations (1)
Hôpital des Trois-Chêne (HUG)
🇨🇭Geneva, Thônex, Switzerland