Transthoracic Ultrasound Elastography in Pulmonary Lesions and Diseases
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Elastography
- Sponsor
- National Taiwan University Hospital
- Enrollment
- 45
- Locations
- 1
- Primary Endpoint
- Comparison of strain ratio between necrosis, atelectasis, consolidation and tumor
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
Elastography is an imaging of tissue elasticity or stiffness and is currently emerging as a mainstream tool for ultrasound-based diagnosis. This compressibility property of materials, mathematically expressed as the change in tissue displacement as a function of its distance from the compressing device, is known as strain and is the parameter that is imaged in an elastogram.
Elastography has currently shown promising result in differentiating viscoelastic nature of various organs, which is a consequence of certain underlying diseases.
At present, there are limited literatures revealing the application and feasibility of ultrasonic elastography in lung lesions. This is essentially important as it may serve as an adjuvant to B-mode ultrasound. The investigators aimed at exploring the application and feasibility of ultrasonic elastography on lung lesions.
Detailed Description
Patients performed conventional B-mode ultrasound, subsequently followed by ultrasound elastography. The strain ration was measured and was compared between necrosis, atelectasis, consolidation and tumor.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients with radiographic findings of:
- •consolidation
- •obstructive pneumonitis
Exclusion Criteria
- •Patients with poor acoustic window
- •Unable to hold breathing
- •Not cooperative
- •Presence of pleural effusion
Outcomes
Primary Outcomes
Comparison of strain ratio between necrosis, atelectasis, consolidation and tumor
Time Frame: Up to 15 months
The strain ratio was measured under ultrasonic elastography. At least three measurements were performed each time and we average all the measurements as the final strain ratio. Independent t test was used for comparison.