MedPath

Accelerated PrEP Access for Black MSM and TW

Not Applicable
Withdrawn
Conditions
HIV/AIDS
Interventions
Registration Number
NCT04329442
Lead Sponsor
University of Chicago
Brief Summary

The investigators will pilot-test an accelerated PrEP initiation approach among young high-risk Black/African American (B/AA) men who have sex with men (MSM) and transgender women (YMSM/TW) at the point of care in community contexts.

Detailed Description

The study team will provide a free 30-day supply of HIV pre-exposure prophylaxis (PrEP) to young Black MSM and TW identified as PrEP-eligible and interested in taking PrEP to reduce their risk of HIV acquisition. This intervention is intended to assist youth at high risk for HIV acquisition in successfully initiating PrEP use.

Recruitment & Eligibility

Status
WITHDRAWN
Sex
Male
Target Recruitment
Not specified
Inclusion Criteria
  1. ages 18-24;
  2. assigned male at birth, identify as a man (cisgender), transgender woman, or gender non-conforming or genderqueer;
  3. identifying as Black, African American, or multiracial with at least one parent identifying as Black or African American;
  4. not currently taking PrEP or attending a visit to initiate PrEP;
  5. self-report being HIV-negative;
  6. reporting one of the following HIV risks in the last 6 months (Hosek, Rudy et al. 2015, Hosek, Rudy et al. 2017): a. condomless anal intercourse with an HIV-infected male partner or a male partner of unknown HIV status; b. anal intercourse with 3 or more male sex partners; c. exchange of money, gifts, shelter, or drugs for anal sex with a male partner; d. sex with a male partner and has had a sexually transmitted infection; e. sexual partner of an HIV-infected male with whom condoms were not consistently used; f. anal intercourse where the condom broke or slipped off
Exclusion Criteria
  • We are excluding those individuals who were assigned female at birth (female birth certificate) and/or cis-gender women (those assigned female at birth and identify as women) from the all phases of this study as this study is intended to explore the HIV prevention behaviors of B/AA young men who have sex with men and young transgender women (assigned male at birth) as these two groups represent the highest risk groups for HIV infection in the US, yet only a small percentage are aware or currently use PrEP for HIV prevention.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
PrEP ReceivedEmtricitabine / Tenofovir Disoproxil Oral TabletParticipants will be provided with a free 30-day supply of PrEP.
Primary Outcome Measures
NameTimeMethod
Intention to Continue PrEPPost Intervention (4 months after receiving intervention)

Intention to continue use of PrEP will be assessed via survey questions related to a respondent having made a follow-up appointment to continue taking PrEP, attended an appointment to continue taking PrEP, having filled a prescription for PrEP, and reporting an interest in continuing PrEP after current supply is complete.

PrEP AdherencePost Intervention (4 months after receiving intervention)

PrEP adherence will be assessed via self-report of how many pills from the initial intervention remain and a self-assessment of success at remembering to take PrEP daily.

Secondary Outcome Measures
NameTimeMethod
PrEP Adherence Self-EfficacyPost Intervention (4 months after receiving intervention)

PrEP adherence self-efficacy will be assessed via a 9-question scale focused on respondents' belief that they could continue to take PrEP when experiencing barriers to adherence. Each item is scored on a 0-10 scale, where 0 means "cannot do at all" and 10 means "completely certainly can do." This scale has been adapted from the Adherence Self-Efficacy Scale (Johnson et al., 2007).

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