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临床试验/IRCT138801161788N1
IRCT138801161788N1已完成2 期

Impact of therapeutic writing on quality of life and psychological distress in patients with vitiligo

Iran University of Medical Sciences0 个研究点目标入组 72 人开始时间: 待定最近更新:
适应症

试验速览

阶段
2 期
状态
已完成
入组人数
72

研究概览

简要总结

Background:
In this clinical trial, we examined whether or not expressive writing as a psychological
intervention reduces psychological distress in vitiligo patients receiving phototherapy.
Methods:
A total of 139 adult vitiligo patients were asked to complete the GHQ-28 in order
to identify their psychiatric disturbances. The GHQ-28 scores showed that 78 patients (56.5%)
had psychiatric distress. They were later enrolled in this randomized controlled trial conducted
during June 2009 until Dec. 2009 at Razi Hospital in Tehran. Patients were randomly divided
into 2 groups. Group A underwent the routine treatment protocol. Group B did the same, but they
were also instructed to practice ‘expressive writing’. The intervention continued 4 weeks. After 4
weeks, patients in both groups were re-evaluated using the GHQ-28.
Results:
The overall GHQ-28 scores and sub-scores were significantly reduced in both groups A
(47.9+/-11.71, P=0.000) and B (48.94+/-10.69, P=0.000) after 4 weeks of intervention. However,
no statistically significance difference was found between the two groups in terms of their overall
scores (P=0.7) and their sub-scores.
Conclusion:
The effect of expressive writing on reducing psychological distress in patients with
vitiligo remains equivocal. Nonetheless, further studies with larger sample sizes and of longer
duration especially in non-western cultural contexts are recommended

研究设计

研究类型
Interventional

入排标准

年龄范围
18 years 至 80 years(—)
性别
All

入选标准

  • Inclusion Criteria: Age>18 years, lasting more than 6 month after diagnosis, literacy at least primary school

排除标准

  • psychosis, systemic and chronic illness, no consent to participate in study

研究者

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