T2 Weighted Imaging of the Liver With Fast Spin Echo MRI

Not Applicable

Terminated

• Conditions: Liver Disease
• Interventions: Device: MRI examinations

• Registration Number: NCT02186054
• Lead Sponsor: Ottawa Hospital Research Institute

Brief Summary

The purpose of this study is to test two new MRI (magnetic resonance imaging) sequences to see how they compare to previously used imaging sequences as they may improve the quality of abdominal MRI.

Detailed Description

* Approximately 50 patients undergoing routine liver MRI in our practice imaged with one of our 4 clinical scanners will undergo our standard liver MRI protocol with the addition of 2 breath-hold sequences (FSE Flex and eSSFSE) only increasing the scan time by approximately 3 minutes.

* Data will be retrieved from examinations that have been performed from the patient's electronic imaging file stored in our picture archiving and communication system (PACS).

* Images will be completely anonymized. No patient identifiers will be available on the images during the analysis.

* Analyses will include the visual assessment of image quality, presence and severity of imaging artifact and other non-invasive imaging outcomes performed by radiologists blinded to patient information and the type of sequence performed. Data will be presented in a Likert type scale (1=poor, 2=suboptimal, 3=average, 4=above average and 5=excellent) and imaging parameters will be compared using the Wilcoxon sign rank test.

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2014-06
• Study First Submitted: 2014-07-04
• Study First Submitted QC: 2014-07-04
• Study First Posted: 2014-07-10
• Status Verified: 2015-11
• Last Update Submitted: 2015-11-17
• Last Update Posted: 2015-11-18
• Primary Completion: 2016-06
• Study Completion: 2016-06

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Patients undergoing routine liver MRI imaged with one of our 4 clinical scanners (MR 750W, General Electric, Milwaukee WI)

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Exclusion Criteria

• Patients not undergoing routine liver MRI

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Imaging- MRI examinations	MRI examinations	Liver MRI imaging will be performed on 50 patients.

Primary Outcome Measures

Name	Time	Method
The number of abdominal MRI scans deemed improved quality	Regular scan time with one of 4 clinical scanners plus 3 additional minutes	Data is presented in a Likert type scale (1=poor, 2=suboptimal, 3=average, 4=above average and 5=excellent) and imaging parameters are compared using the Wilcoxon sign rank test.

Secondary Outcome Measures

Name	Time	Method
The number of MRI scans that display severity of imaging artifact	Regular scan time with one of 4 clinical scanners plus 3 additional minutes	Data is presented in a Likert type scale (1=poor, 2=suboptimal, 3=average, 4=above average and 5=excellent) and imaging parameters are compared using the Wilcoxon sign rank test.

Trial Locations

Locations (1)

Ottawa Hospital (Civic Campus); 🇨🇦 Ottawa, Ontario, Canada