Effects of black tea with and without a fat load on vascular function in mildly hypertensive volunteers

Not Applicable

Completed

• Conditions: Hypertension and arterial stiffness; Circulatory System; Essential (primary) hypertension

• Registration Number: ISRCTN27687092
• Lead Sponsor: nilever Food and Health Research Institute (UFHRI) (Netherlands)

Brief Summary

2015 results in: https://www.ncbi.nlm.nih.gov/pubmed/25658240

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2011-03-01
• Study Start: 2014-05-20
• Last Update Posted: 29 April 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1. Never-treated essential hypertensive (EH) patients referred to the outpatient unit Centre of Hypertension and Cardiovascular Prevention of L?Aquila
2. = 18 and = 75 years of age
3. Non-diabetic
4. SBP between 140 and 159 mmHg or DBP between 90 and 99 mmHg
5. Body mass index between 19 and 31 kg/m2

Exclusion Criteria

1. Being an employee of the Department of Internal Medicine and Public Health of the University of L'Aguila
2. Except for grade I hypertension no additional cardiovascular risk factors (including a recorded history of coronary infarction, vascular surgery, transient ischemic attack, left ventricular hypertrophy or cardiac arrhythmia or apparent family history of cardiovascular diseases)
3. A recorded history or current metabolic diseases, chronic gastrointestinal disorders, cardiovascular or renal disease or diabetes mellitus
4. Indications for compromised liver or kidney function.
5. Currently on a medically prescribed diet or slimming diet
6. Subjects with irregular pulse or pulse =50 or =100 bpm
7. Reported intense sporting activities > 10 hours/week
8. Subjects who are taking prescribed medical treatment that is likely to affect blood pressure (or who have been taking such medication in the past)
9. Use of systemic antibiotics in the period of 3 months prior to the study
10. Recent blood donation i.e. 1 month (male subjects) or 2 months (females) prior to the study and no planned blood donation during the study period
11. Reported intolerance or allergy to constituents of the study products
12. Reported lactating, pregnant or wishing to become pregnant during the study
13. Reported weight change ± 10% during a period of 6 months prior to the study
14. Reported participation in another biomedical study 3 months before the start or during the study
15. Reported smoking during a period of one year prior to the study or planning to smoke during the study
16. Reported participation in night shift work
17. Female participants not in post-menopausal phase

Study & Design

• Study Type: Interventional
• Study Design: Not specified