ACTRN12611001290987已完成4 期
Sodium Bicarbonate To Prevent Increases in Serum Creatinine After Orthotopic Liver Transplantation: a Pilot Double-Blind, Randomized Controlled Trial.
Austin Hospital0 个研究点目标入组 60 人开始时间: 2011年12月16日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Prevention
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 75 Years（—）
- 性别
- All
入选标准
- •Adult patients undergoing orthotopic liver transplantation
排除标准
- •1. End stage renal disease (plasma creatinine >300 mmol/L)
- •2. Preoperative renal replacement therapy
- •3. Intraoperative continuous veno-veno haemofiltration
- •4. Combined liver-kidney transplant
- •5. Fulminant hepatic failure
- •6. Congestive cardiac failure
- •7. Preoperative hypernatraemia (serum sodium > 150 mmol/L)
- •8. Preoperative hyponatraemia (serum sodium < 130 mmol/L) concerns with central pontine myelinosis from additional Sodium load from study solution.
- •9. Preoperative hypokalaemia (serum potassium < 3.0 mmol/L)
- •10. Informed consent not obtained
- •11. Pregnancy
研究者
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