Evaluation of the Level of Middle Cranial Fossa Dura in Patients With Cholesteatoma
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Assiut University
- Enrollment
- 80
- Primary Endpoint
- Evaluation of the Level of Middle Cranial Fossa Dura in Patients with Cholesteatoma by multislice computed tomography.
Study Overview
Brief Summary
Cholesteatoma is a destructive lesion that progressively expands in the middle ear, mastoid or petrous bone and leads to destruction of the nearby structures. Erosion, which is caused by bone resorption of the ossicular chain and otic capsule, may cause hearing loss, vestibular dysfunction, facial paralysis and intracranial manifestations
Detailed Description
Cholesteatoma has three Classical forms: (1) Congenital, primary or genuine cholesteatoma: occurs behind an intact tympanic membrane. Primary acquired cholesteatoma: looks like a limited diverticulum of the pars flaccida with little or no history of otorrhea. Secondary acquired cholesteatoma: develops with posterosuperior perforations in eardrum and expansion of the disease process into the antrum, mastoid, attic and middle ear. Granulation tissue, polyps and foul- smelling otorrhea are common findings in this type
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •All adults above the age of 18 presented to the Assiut university Clinic with
- •cholesteatoma will be included in the study.
Exclusion Criteria
- •Patients with previous mastoid surgery
- •Patients with Craniofacial anomalies or cleft lip and palate
- •Pediatric populations ≤ 18 years old
- •Patients with congenital ear anomalies
Outcomes
Primary Outcomes
Evaluation of the Level of Middle Cranial Fossa Dura in Patients with Cholesteatoma by multislice computed tomography.
Time Frame: One year
determination the level of tegmen in patients with attico-antral diseases by MSCT
Secondary Outcomes
No secondary outcomes reported
Investigators
Mariam Zakaria
Principal investigator
Assiut University