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Clinical Trials/NCT04551612
NCT04551612
Unknown
Not Applicable

Evaluation of the Level of Middle Cranial Fossa Dura in Patients With Cholesteatoma

Assiut University0 sites80 target enrollmentOctober 1, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cholesteatoma, Middle Ear
Sponsor
Assiut University
Enrollment
80
Primary Endpoint
Evaluation of the Level of Middle Cranial Fossa Dura in Patients with Cholesteatoma by multislice computed tomography.
Last Updated
5 years ago

Overview

Brief Summary

Cholesteatoma is a destructive lesion that progressively expands in the middle ear, mastoid or petrous bone and leads to destruction of the nearby structures. Erosion, which is caused by bone resorption of the ossicular chain and otic capsule, may cause hearing loss, vestibular dysfunction, facial paralysis and intracranial manifestations

Detailed Description

Cholesteatoma has three Classical forms: (1) Congenital, primary or genuine cholesteatoma: occurs behind an intact tympanic membrane. Primary acquired cholesteatoma: looks like a limited diverticulum of the pars flaccida with little or no history of otorrhea. Secondary acquired cholesteatoma: develops with posterosuperior perforations in eardrum and expansion of the disease process into the antrum, mastoid, attic and middle ear. Granulation tissue, polyps and foul- smelling otorrhea are common findings in this type

Registry
clinicaltrials.gov
Start Date
October 1, 2020
End Date
October 1, 2022
Last Updated
5 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mariam Zakaria

Principal investigator

Assiut University

Eligibility Criteria

Inclusion Criteria

  • All adults above the age of 18 presented to the Assiut university Clinic with
  • cholesteatoma will be included in the study.

Exclusion Criteria

  • Patients with previous mastoid surgery
  • Patients with Craniofacial anomalies or cleft lip and palate
  • Pediatric populations ≤ 18 years old
  • Patients with congenital ear anomalies

Outcomes

Primary Outcomes

Evaluation of the Level of Middle Cranial Fossa Dura in Patients with Cholesteatoma by multislice computed tomography.

Time Frame: One year

determination the level of tegmen in patients with attico-antral diseases by MSCT

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