Evaluation of the Level of Middle Cranial Fossa Dura in Patients With Cholesteatoma
试验速览
- 阶段
- 不适用
- 入组人数
- 80
- 主要终点
- Evaluation of the Level of Middle Cranial Fossa Dura in Patients with Cholesteatoma by multislice computed tomography.
研究概览
简要总结
Cholesteatoma is a destructive lesion that progressively expands in the middle ear, mastoid or petrous bone and leads to destruction of the nearby structures. Erosion, which is caused by bone resorption of the ossicular chain and otic capsule, may cause hearing loss, vestibular dysfunction, facial paralysis and intracranial manifestations
详细描述
Cholesteatoma has three Classical forms: (1) Congenital, primary or genuine cholesteatoma: occurs behind an intact tympanic membrane. Primary acquired cholesteatoma: looks like a limited diverticulum of the pars flaccida with little or no history of otorrhea. Secondary acquired cholesteatoma: develops with posterosuperior perforations in eardrum and expansion of the disease process into the antrum, mastoid, attic and middle ear. Granulation tissue, polyps and foul- smelling otorrhea are common findings in this type
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All adults above the age of 18 presented to the Assiut university Clinic with
- •cholesteatoma will be included in the study.
排除标准
- •Patients with previous mastoid surgery
- •Patients with Craniofacial anomalies or cleft lip and palate
- •Pediatric populations ≤ 18 years old
- •Patients with congenital ear anomalies
结局指标
主要结局
Evaluation of the Level of Middle Cranial Fossa Dura in Patients with Cholesteatoma by multislice computed tomography.
时间窗: One year
determination the level of tegmen in patients with attico-antral diseases by MSCT
次要结局
未报告次要终点
研究者
Mariam Zakaria
Principal investigator
Assiut University