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Clinical Trials/NCT03129802
NCT03129802
Unknown
Not Applicable

Incidence and Risk Factors of Extubation Failure in Pediatric Resuscitation

University Hospital, Strasbourg, France1 site in 1 country60 target enrollmentJuly 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Respiratory Insufficiency
Sponsor
University Hospital, Strasbourg, France
Enrollment
60
Locations
1
Primary Endpoint
Failure of extubation
Last Updated
8 years ago

Overview

Brief Summary

The failure of extubation in pediatric resuscitation is most often described as the need for reintubation within 48 hours after extubation. The failure rate of extubation in pediatric intensive care varies in the literature there is 4 to 22% failure. These failures result in increased mortality, morbidity with a use of larger tracheostomy, a prolonged residence time. Some risk factors are well defined in the literature as the duration of intubation, ENT and neurological history, the persistence of a respiratory disease, a high level of sedation. Other factors are more controversial as age, ventilatory parameters just before extubation before extubation blood gases, the interest of a leak test.

Also pediatric populations are extremely heterogeneous, so the investigators would like to highlight to extubation failure risk factors in Hautepierre pediatric ICU to better support these high-risk children.

Registry
clinicaltrials.gov
Start Date
July 2016
End Date
August 2017
Last Updated
8 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
University Hospital, Strasbourg, France
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Children hospitalized in pediatric intensive care, under 18 years, intubated, ventilated for more than 2 hours and for which planning extubation or intubated children for whom an unplanned extubation just happened.
  • Children whose holding parental authority are not opposed to the use of clinical data from their child for research purposes.

Exclusion Criteria

  • Refusal to participate in the study

Outcomes

Primary Outcomes

Failure of extubation

Time Frame: need for a new intubation within the first 48 hours after extubation

Study Sites (1)

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