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Clinical Trials/NCT02018484
NCT02018484
Completed
Not Applicable

Positioning of the Tibial Cut in Unicompartmental Medial Knee Replacement by Using Patient Specific Cutting Guides.

Rennes University Hospital1 site in 1 country32 target enrollmentDecember 2013
ConditionsKnee Prosthesis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Knee Prosthesis
Sponsor
Rennes University Hospital
Enrollment
32
Locations
1
Primary Endpoint
Success rate in performing the tibial cut
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

Unicompartmental knee replacements are performed to treat osteoarthritis or osteonecrosis of the knee especially when it affects only the medial femoro-tibial compartment. To place the prosthesis, bone removal is necessary. The orientations of the bony cuts directly influence the position of the different elements of the prosthesis and the limb alignment. It is known that good positioning of the prosthesis is the key of a good survival of the implants. To guide the blade of the saw, cutting guides are used. The position of these guides gives the final position of the cuts. At present, two main techniques are used to position the guides: the conventional one, not very costly but not very accurate, and the navigated procedure, which is more accurate but also more expensive and more invasive. Since few years, patient specific cutting guides are used in total knee replacement with encouraging results and more recently in uni compartmental knee replacement with no scientific proof of efficiency.

This study aims to validate the procedure of patient specific cutting guides.

Detailed Description

30 patients will be included in a mono centric, single-arm study with evaluation of the primary outcome by an independent expert comity. Each participant will have an MRI which will be sent to the society in charge of creating the patient specific cutting guides. The intervention will be performed using the patient specific cutting guides and in parallel, a station of navigation will be used to provide a safety control of the orientation of the cutting guide and to collect per operative data. Evaluation visit is performed 6 months after surgery.

Registry
clinicaltrials.gov
Start Date
December 2013
End Date
May 2016
Last Updated
9 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Rennes University Hospital
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • patients aged 18 or older;
  • indication of medial unicompartmental knee replacement (validated by the orthopedic surgeons staff) ;
  • written informed consent.

Exclusion Criteria

  • MRI contraindication ;
  • Absence of the main investigator or the associated scientist during the surgical procedure ;
  • Adults under legal protective regimen or deprived of liberty.

Outcomes

Primary Outcomes

Success rate in performing the tibial cut

Time Frame: Month 6

Success is defined as a correct orientation of the tibial cut which has to be within patient's target value (± 2°) at 6 months in both the frontal and the sagittal plans. Failure of prosthesis implantation (defined by outranging patient's target value of more than 4º in the frontal or the sagittal plan or more than 3 mm on the cutting depth, controled by per operative navigated procedure) is considered as treatment failure.

Secondary Outcomes

  • Success rate in conserving a residual varus.(Month 6)
  • Variations of other orientation parameters of the tibial cut and limb alignment at the different times of the procedure (per and post operative) .(Per-operative, and Month 6)

Study Sites (1)

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