The effect of a paracervical block prior to total laparoscopic hysterectomy on patient's quality of recovery.

Phase 2

Recruiting

• Conditions: Post operative pain; Hysterectomy; Anaesthesiology - Pain management; Surgery - Other surgery; Reproductive Health and Childbirth - Other reproductive health and childbirth disorders

• Registration Number: ACTRN12621000584831
• Lead Sponsor: St John of God Subiaco Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-05-17
• Last Update Posted: 17 April 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 94

Inclusion Criteria

1.Women undergoing a total laparoscopic hysterectomy (TLH) plus or mimus bilateral
Salpingo-oophorectomy (BSO) for any of the following conditions:
a. Heavy menstrual bleeding/ abnormal uterine bleeding
b. Stage 1 and 2 Endometriosis
c. Adenomyosis
d. Risk reduction surgery e.g. carriers of BRCA1/2 gene faults, Lynch Syndrome or
women considered high risk due to family history
e. Complex adnexal masses not suspicious for malignancy
f. Early stage cervical cancer requiring simple hysterectomy

2.Patients aged 18 years of age and over

3.Fluent in English

Exclusion Criteria

1.Chronic pelvic pain

2.Recent opioid use (4 weeks prior to surgery)

3.Deeply infiltrative endometriosis (evidence of nodular disease on USS) or endometrioma.

4.Allergies to protocol drugs

5.Endometrial cancer

6.Patient requiring comprehensive surgical staging of malignant disease

7.Previous midline laparotomy

8.BMI >40kg/m2

9.Renal impairment (eGFR< 60 or Cr > 100)

10.Hepatic impairment (ALT> 40 or AST > 40)

11.Alcohol and drug dependency

12.Pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified