Relationship Between Uterocervical Angle and Prediction of Spontaneous Preterm Birth
试验速览
- 阶段
- 不适用
- 入组人数
- 197
- 主要终点
- Gestational age at birth
研究概览
简要总结
To determine whether a novel ultrasonographic marker, uterocervical angle, correlates with risk of spontaneous preterm birth
详细描述
The uterocervical angle is the triangular segment measured between the lower uterine segment and the cervical canal, yielding a measurable angle. The first ray was placed from the internal os to the external os. The calipers were placed where the anterior and posterior walls of the cervix touch the internal and external os along the endocervical canal. If the cervix was curved, the first ray was also drawn from the internal os to the external os as a straight line. A second ray was then drawn to delineate the lower uterine segment. This ray was traced up the anterior uterine segment to a distance allowed by the preloaded image. Ideally, the second ray would reach 3cm up the lower uterine segment in order to establish an adequate measurement. The anterior angle in between the two rays was measured with a protractor. In the presence of funneling, the first ray was placed to measure the length of remaining cervix. The second caliper was placed from the innermost portion of measurable cervix and extended to the lower uterine segment. In the event that the lower uterine segment was found to be irregular, the second caliper was placed centrally along the segment. In the event of a retroverted uterus, the angle should be measured in a similar fashion with the first ray along the measurable cervix and the second ray traced along the lower uterine segment. Unlike in an anteverted or axial positioned uterus, however, the posterior side of the angle closer to the intrauterine contents should then be measured.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 40 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Maternal age (18_40).
- •BMI (20_34).
- •singleton gestations between (18 - 28) weeks.
- •Multiparity.
- •History of previous preterm deliveries or mid-trimesteric abortions.
排除标准
- •Loss of follow up.
- •Preterm premature rupture of membranes(PPROM).
- •Placental abnormalities.
- •Past history of cervical operations.
- •Multifetal pregnancy.
- •Polyhydramnios.
- •Steroids intake .
- •Medically or obstetric indicated pregnancy termination.
- •Serious maternal or fetal problems.
- •Cerclage during current pregnancy before the screening.
结局指标
主要结局
Gestational age at birth
时间窗: 6 months
Preterm labour is defined as regular contractions of the uterus resulting in changes in the cervix that start before 37 weeks of pregnancy. Changes in the cervix include effacement (the cervix thins out) and dilation (the cervix opens so that the fetus can enter the birth canal).
次要结局
- Apgar score at 1 and 5 minutes(6 months)
研究者
Mohammed Shaaban Abd Al Razik Ibrahim
Principal investigator
Ain Shams Maternity Hospital
