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临床试验/NCT04532086
NCT04532086Unknown不适用

Relationship Between Uterocervical Angle and Prediction of Spontaneous Preterm Birth

Ain Shams Maternity Hospital0 个研究点目标入组 197 人开始时间: 2020年11月20日最近更新:
适应症

试验速览

阶段
不适用
入组人数
197
主要终点
Gestational age at birth

研究概览

简要总结

To determine whether a novel ultrasonographic marker, uterocervical angle, correlates with risk of spontaneous preterm birth

详细描述

The uterocervical angle is the triangular segment measured between the lower uterine segment and the cervical canal, yielding a measurable angle. The first ray was placed from the internal os to the external os. The calipers were placed where the anterior and posterior walls of the cervix touch the internal and external os along the endocervical canal. If the cervix was curved, the first ray was also drawn from the internal os to the external os as a straight line. A second ray was then drawn to delineate the lower uterine segment. This ray was traced up the anterior uterine segment to a distance allowed by the preloaded image. Ideally, the second ray would reach 3cm up the lower uterine segment in order to establish an adequate measurement. The anterior angle in between the two rays was measured with a protractor. In the presence of funneling, the first ray was placed to measure the length of remaining cervix. The second caliper was placed from the innermost portion of measurable cervix and extended to the lower uterine segment. In the event that the lower uterine segment was found to be irregular, the second caliper was placed centrally along the segment. In the event of a retroverted uterus, the angle should be measured in a similar fashion with the first ray along the measurable cervix and the second ray traced along the lower uterine segment. Unlike in an anteverted or axial positioned uterus, however, the posterior side of the angle closer to the intrauterine contents should then be measured.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Maternal age (18_40).
  • BMI (20_34).
  • singleton gestations between (18 - 28) weeks.
  • Multiparity.
  • History of previous preterm deliveries or mid-trimesteric abortions.

排除标准

  • Loss of follow up.
  • Preterm premature rupture of membranes(PPROM).
  • Placental abnormalities.
  • Past history of cervical operations.
  • Multifetal pregnancy.
  • Polyhydramnios.
  • Steroids intake .
  • Medically or obstetric indicated pregnancy termination.
  • Serious maternal or fetal problems.
  • Cerclage during current pregnancy before the screening.

结局指标

主要结局

Gestational age at birth

时间窗: 6 months

Preterm labour is defined as regular contractions of the uterus resulting in changes in the cervix that start before 37 weeks of pregnancy. Changes in the cervix include effacement (the cervix thins out) and dilation (the cervix opens so that the fetus can enter the birth canal).

次要结局

  • Apgar score at 1 and 5 minutes(6 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mohammed Shaaban Abd Al Razik Ibrahim

Principal investigator

Ain Shams Maternity Hospital

相似试验

Uterocervical Angle and Preterm Labour | 临床试验