To compare the effectiveness of Dexmedetomidine vs Ketamine along with local anaesthetic Ropivacaine in blocking scalp nerves for awake brain surgeries
Not Applicable
- Conditions
- Health Condition 1: C713- Malignant neoplasm of parietal lobe
- Registration Number
- CTRI/2024/01/061259
- Lead Sponsor
- Ankur Luthra
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
46 ASA I and II patients aged between 18-65 years scheduled for Elective Awake Craniotomy surgery for brain tumors will be enrolled in this study
Exclusion Criteria
i.Refusal of consent
ii.Known allergy to Dexmedetomidine or Ketamine
iii.Prior Craniotomy / Chronic analgesic use
iv. Coagulopathy
v. Schizophrenia or bipolar disorders
vi. Uncontrolled anxiety or depression
vii. Hepatic or Renal impairment (Stage III or IV)
viii. BMI >35 kg/m2
ix. Significant Respiratory disease (COPD or Asthma requiring daily therapy)
x. Significant Cardiovascular disease (2nd/3rd degree heart block, Congestive heart failure, symptomatic coronary artery disease)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to first request of rescue analgesic drug by the patient in the postoperative period which is defined as the time interval between onset of sensory blockade to the first use of rescue analgesic drug as demanded by the patient (NRS more than 4)Timepoint: Within 24 hours whenever NRS more than 4
- Secondary Outcome Measures
Name Time Method