Comparing two drugs for prevention of sore throat after laparoscopic surgery

Not Applicable

• Conditions: Health Condition 1: C679- Malignant neoplasm of bladder, unspecified

• Registration Number: CTRI/2020/01/022922
• Lead Sponsor: Dr Divya Abhishek Kishore

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

ASA physical status I-III,

Undergoing elective laparoscopic surgery in Trendelenburg position

Requiring endotracheal intubation

Duration of surgery >90minutes

Expected to remain admitted in the hospital for >24hours.

Exclusion Criteria

Patients with preexisting sore throat/ hoarsen

· ASA physical status IV

· BMI > 30

· Vocal performer by occupation

· Recent or recurrent respiratory tract infection

·Risk of postoperative aspiration (obesity, pregnancy )

· Pain medications, corticosteroids ; calcium channel blocker

· 2nd and 3rd degree Heart block 

· Allergy to Study drugs

·Anticipated difficult intubation(Mallampati grade >2, difficult mask ventilation requiring oral/nasal airway, Cormack and Lehane grade III-IV) Intubation attempt >1

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Post operative sore throatTimepoint: 15min,1h,6h,12h,24h

Secondary Outcome Measures

Name	Time	Method
Bloodstain over endotracheal tubeTimepoint: 30 sec post extubation;Percentage of glottic opening scoreTimepoint: 2 seconds before endotracheal intubation;Post operative sore throat on swallowingTimepoint: 15min,1h,6h,12h,24h;Total morphine consumptionTimepoint: 24h after surgery