A STUDY FOR COMPARING THE EFFECT OF MIFEPRISTONE WITH MISOPROSTOL FOR INDUCTION OF LABOR
Not Applicable
- Conditions
- Health Condition 1: null- pregnant women for induction of labor
- Registration Number
- CTRI/2013/11/004151
- Lead Sponsor
- Govt of HP
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
Women admitted with indications for induction of labor from gestation 37 to 42 weeks.
2. Induction can be postponed for 48 hours.
3. Bishop score <= 6.
4. Singleton pregnancy.
5. Vertex presentation.
6. Maternal age > 18 years.
Exclusion Criteria
Bishop score > 6.
2. Contraindications to vaginal delivery.
3. Oligohydramnios, IUGR.
4. Any previous cesarean section or uterine surgery.
5. Gravida >= 4.
6. Multiple pregnancies.
7. Severe pre eclampsia.
9. Renal failure, adrenal insufficiency, liver failure.
10. Patient on corticosteroid treatment.
11. Blood clotting disease or on anticoagulant therapy.
12. Intrauterine fetal death.
13. Any history suggestive of drug allergy.
14. Abruptio placentae
15. Non-reassuring fetal heart rate status.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of women entering labor after use of mifepristone alone after 24 & 48 hoursTimepoint: time from induction of labor to delivery
- Secondary Outcome Measures
Name Time Method â?¢Proportion of women vaginally delivered in each group <br/ ><br>â?¢Proportion of women with cesarean section in each group <br/ ><br>â?¢Proportion of women with failed induction in either group <br/ ><br>â?¢Duration of labor in women in each group <br/ ><br>â?¢Need and amount of oxytocin required in each group <br/ ><br>â?¢Neonatal outcomes including ; <br/ ><br>ï??Apgar score (1 min & 5 min) <br/ ><br>ï??Need of phototherapy (if required; duration) <br/ ><br>ï??Intensive care admission (if required) <br/ ><br>â?? <br/ ><br>Timepoint: time from induction of labor to delivery