Monash Cognition Imaging Study (MCIS): Characterising Mild Cognitive Impairment using multimodal biomarkers

Not Applicable

Recruiting

• Conditions: Mild Cognitive Impairment; Neurological - Dementias

• Registration Number: ACTRN12620001246976
• Lead Sponsor: Alfred Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-11-20
• Last Update Posted: 30 November 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1.Age 30-85 years
2.At least 6 years of education
3.Adequate English, visual & auditory acuity to complete cognitive testing
4.Reliable study partner
5.Subjective and objective cognitive impairment consistent with MCI
6.Potentially interested in participation in therapeutic drug trials

Exclusion Criteria

1.Lifetime history of schizophrenia, schizoaffective disorder, or bipolar disorder.
2.Current major depressive episode or a past history of major depressive disorder with a high risk of relapse in the opinion of the investigator
3.Current drug or alcohol abuse/dependence.
4.History of alcohol abuse/dependence within 2 years of the onset of the symptoms of cognitive impairment.
5.Participants with a history of cancer (other than skin or in situ prostate cancer) within the previous 5 years.
6.Any significant disease or unstable medical condition that could affect cognitive testing or longevity (i.e., chronic renal failure, chronic hepatic disease, severe pulmonary disease).
7.Other neurological illness, including clinically significant stroke or Parkinson’s disease. A history of stable epilepsy is not an exclusion criterion.
8.Participants in whom magnetic resonance imaging (MRI) is contraindicated.

Study & Design

• Study Type: Interventional
• Study Design: Not specified