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临床试验/NCT07035795
NCT07035795招募中不适用

Cardiovascular Physiological Signal Recording Project

Chinese University of Hong Kong1 个研究点 分布在 1 个国家目标入组 198 人开始时间: 2025年5月14日最近更新:

试验速览

阶段
不适用
状态
招募中
入组人数
198
试验地点
1
主要终点
Development of a model using PPG and rPPG

研究概览

简要总结

Vital sign monitoring is important for patients, especially those with underlying cardiovascular diseases. Traditional monitoring including SaO2, blood pressure, pulse, rhythm monitoring can be cumbersome, with wires and cuff attached to a patient. This can lead to reduced compliance, especially in uncooperative patients or young kids. The use of photoplethysmography (PPG) is simple and is widely used clinically to achieve continuous monitoring of SaO2, respiratory rate and pulse rate. PPG also contains important physiological signals that can correlate with blood pressure.

Remote PPG (rPPG) with can be collected by cameras. This is being developed to achieve contactless monitoring. Theoretically, by analyzing video recording, the fluctuation of intensity of lights reflected from patients' body surface can be measured. Physiological parameters such as heart rate, SaO2, and blood pressure can then be calculated. However, because of environmental signal contamination, motion artefacts and other limitations, rPPG remains inaccurate for routine clinical use. To improve accuracy of PPG recordings, machine learning approach has been attempted. This study aims to gather physiological data from patients to train these models.

详细描述

This is an observational study. The physiological signal collected includes blood pressure, pulse rate, respiratory rate, SaO2, cardiac rhythm. PPG signals will be extracted from dedicated devices such as commercially available SaO2 monitors. Remote PPG signals will be collected if patient consent for video recording.

Patient demographic data, including age, sex, past medical history, medication history, body weight and height, etc, may be collected to validate training of this model.

After collection of these data, machine learning approach will be used to analyze these recordings and correlate them with PPG and rPPG data.

After their enrollment, during the duration of the study, patient's electronic record may be accessed in the next 5 years to explore any association of PPG or rPPG signals and long term outcome.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients > 18 years old
  • Has a known medical disease
  • Able to comply with recording of physiological signals

排除标准

  • Patients who are not able to provide informed consent

结局指标

主要结局

Development of a model using PPG and rPPG

时间窗: through study completion, an average of 4 years

To develop a model using PPG and rPPG to accurately measure physiological signals

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Tam Tsz Kin

Prof

Chinese University of Hong Kong

研究点 (1)

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