Effect of Pathyaputhikadi kashaya and Kankayana gudika in Uterine fibroid

Uterine fibroids also known as Leiomyomas, are smooth tumors of the These are more common in nulliparous or in those having one child infertility. Symptoms include abnormal uterine bleeding, dysmenorrhoea, pelvic pressure, bowel dysfunction , urinary frequency and urgency, urinary retention, low back pain, constipation and dyspareunia.

There is no direct reference for uterine fibroid in Ayurveda. The treatments explained in the context of Gulma and Sula can be taken for the management of uterine fibroid. Pathyaputhikadi kashaya is mentioned in Sahasrayogam with an indication of Arsa, Gulma, Ashteela, Anaha , Sula etc and Kankayana gudika is mentioned in Bhaishajya Ratnavali with an indication of Gulma,Arsa etc are taken for the study.

The study design is an interventional pre and post study, with a sample size of 26. Subjects aged 18 -45 years, diagnosed with Uterine fibroid having pain and bleeding following the inclusion and exclusion criteria will be taken for the study. Data collection will be done by clinical observation through case proforma and relevant investigations will also be done. The medicine will be administered on the following basis. 48 ml of Pathyaputhikadi kashaya before food during intermenstrual phase and 2 tablets (600 mg) of Kankayana gudika with 50 ml milk after food during the bleeding phase, twice daily for 3 consecutive menstrual cycle. The patient will be assessed at the end of each menstrual cycle. Menstrual bleeding is assessed by the Pictorial Blood Loss Assesment Chart (PBAC scale) and pain during menstruation, low back ache, pelvic pressure is assessed by Visual Analogue scale ( VAS). The size of the fibroid is assessed by USG before treatment and after treatment. The data collected will be statistically analysed through appropriate tests and a conclusion will be drawn.