Ventilation in Cardiac Surgery

• Conditions: Anesthesia, General; Respiration, Artificial; Bypass, Cardiopulmonary; Respiratory Complication
• Interventions: Other: Survey

• Registration Number: NCT03255356
• Lead Sponsor: University Hospital, Caen

Brief Summary

The purpose of this study is to evaluate prospectively ventilatory practices in the perioperative cardiac surgery period.

Detailed Description

This is a International Multicentre Observational Trial on all adult cardiac surgery patients with cardiopulmonary bypass (CPB).

Study Timeline

• Status Verified: 2017-03
• Study First Submitted: 2017-06-12
• Study First Submitted QC: 2017-08-18
• Last Update Submitted: 2017-08-18
• Study First Posted: 2017-08-21
• Last Update Posted: 2017-08-21
• Study Start: 2017-11-01
• Primary Completion: 2017-12
• Study Completion: 2017-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• All consecutive cardiac surgery patients with CPB during one predefined period,
• Elective or urgent surgery as defined by EuroSCORE2.

Exclusion Criteria

• Refusal of consent,
• Pregnant women,
• Age < 18 years,
• Heart transplant, ECLS, ventricular assist
• Emergency or salvage surgery as defined by EuroSCORE2

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Cohort	Survey	An anonymised questionnaire will be answered for each includable consecutive patient after verifying the absence of exclusion criteria.

Primary Outcome Measures

Name	Time	Method
incidence of use prophylactic protective mechanical ventilation defined with with low tidal volume (6 to 8 ml / kg based on the ideal body weight)	1 day	percent

Secondary Outcome Measures

Name	Time	Method
incidence of postoperative pulmonary complications	1 month postoperatively	percent
incidence of using positive end-expiratory pressure	1 day	(PEEP)\> 5 cmH2O
incidence of using at least 2 alveolar lung recruitment manoeuvres	1 day	percent
incidence of using a protective ventilation bundle combining prophylactic protective mechanical ventilation and at least 2 alveolar recruitment manoeuvres	1 day	percent

Trial Locations

Locations (10)

CUB Erasm, Université libre de Bruxelles; 🇧🇪 Brussels, Belgium

Universidade Federal de São Paulo (UNIFESP); 🇧🇷 Brasil, Brazil

General University Hospital; 🇨🇿 Praha, Czechia

Caen University Hospital; 🇫🇷 Caen, France

Klinik für Anästhesiologie und Intensivmedizin; 🇩🇪 Jena, Germany

Azienda Ospedaliera Universitaria; 🇮🇹 Pisa, Italy

Osaka city University Graduate school of Medecine; 🇯🇵 Osaki, Japan

VU University Hospital; 🇳🇱 Amsterdam, Netherlands

St Olav University Hospital; 🇳🇴 Trondheim, Norway

Wroclaw Medical University; 🇵🇱 Wrocław, Poland