Comparison between Contact Force Monitoring and Unipolar Signal Modification as a Guide for Catheter Ablation of Atrial Fibrillation: A Prospective Multi-centre Randomized Controlled Study (COMPASS study)
Not Applicable
- Conditions
- Paroxysmal atrial fibrillation
- Registration Number
- JPRN-UMIN000021127
- Lead Sponsor
- Department of Cardiology, Tokyo Women's Medical University
- Brief Summary
nipolar signal modification was superior to contact force monitoring as an endpoint for radiofrequency energy deliveries during pulmonary vein isolation in patients with paroxysmal atrial fibrillation in terms of the 12-month recurrence free rate (85% vs. 70%, p=0.031).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 138
Inclusion Criteria
Not provided
Exclusion Criteria
1) Persistent AF 2) Prior left atrial ablation (surgical or catheter) 3) Left atrial volume >50mm 4) Left ventricular ejection fraction <40% 5) Contraindication to anticoagulation medications 6) Severe pulmonary disease 7) Maintenance dialysis to chronic renal insufficiency
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Ablation success at 1 after after the index procedure. The definition of recurrence; any atrial tachyarrhythmia lasting more than 30 seconds after 3 month after the index procedure. The definition of procedural success; no recurrence without any anti-arrhythmic drugs.
- Secondary Outcome Measures
Name Time Method 1) acute left atrium-pulmonary vein electrical reconnection (time-dependent/ATP-dependent) 2) ablation time 3) energy 4) procedural time 5) complication associated with the procedure 6) contact force value