Comparing Two Methods to Stop Vomiting of Blood Using the Endoscope
Phase 3
Completed
- Conditions
- Portal HypertensionHematemesis
- Interventions
- Procedure: Endoscopic control of hematemesis
- Registration Number
- NCT01131962
- Lead Sponsor
- University of Alexandria
- Brief Summary
Band ligation and injection sclerotherapy are two modalities of treatment that are applied using the endoscope. The purpose of this study is to determine which of two methods is better for controlling bleeding from the upper gut.
- Detailed Description
The use of band ligation for endoscopy during the attack of hematemesis is a novel practice as opposed to injection sclerotherapy.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
- Active hematemesis
- esophageal varices
Exclusion Criteria
- Hemodynamic unstability
- Hepatic coma or precoma
- Tense ascitis
- Coagulopathies
- concomitant gastric varices
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description band ligation group Endoscopic control of hematemesis this group will have immediate control of the hematemesis by endoscopic band ligation. sclerotherapy group Endoscopic control of hematemesis This group will have immediate control of hematemesis by endoscopic sclerotherapy
- Primary Outcome Measures
Name Time Method control of hematemesis 72 hours Success for either techniques to be able to stop the bleeding promptly and maintain that for 72 hours
- Secondary Outcome Measures
Name Time Method occurence of complications from the intervention 30 days the study subjects are reveiwed in 30 days to detect any complications secondary to the endoscopic intervention.
Trial Locations
- Locations (1)
Hematemesis unit, Alexandria Main University Hospital, Azarita
🇪🇬Alexandria, Egypt