Treatment of Non-Alcoholic fatty liver disease by Virechana(Purgation therapy) and Vidangadi Kshara yoga.

Phase 2

Completed

• Conditions: Health Condition 1: K760- Fatty (change of) liver, not elsewhere classified

• Registration Number: CTRI/2022/02/040355
• Lead Sponsor: Institute of Teaching and Research in Ayurveda

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2023-04-15
• Last Update Posted: 13 November 2023

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

Both freshly detected and previously diagnosed cases of NAFLD.

USG findings are suggestive of NAFLD Grade I, II &III.

Exclusion Criteria

aged below 25 years and above 60 years, Pregnant women.Uncontrolled diabetes or hypertension, Complications of Metabolic syndrome-like Cerebrovascular accident, Myocardial Infarction, Chronic Kidney disease.

Ayogya for Virechana karma in group A.

Patients consume hepatotoxic medicines, alcohol, or other narcotic substances. Cirrhosis, Ascites, variceal hemorrhage, coagulopathy, hepatorenal syndrome.

History of viral hepatitis, autoimmune liver diseases (Primary biliary cirrhosis, primary sclerosing cholangitis, autoimmune hepatitis), metabolic disorders (Wilson’s disease, hemochromatosis), HIV, TB other infectious diseases, malignancies, Major psychiatric problems.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Samyaka Virikta Lakshana is to be assessed. <br/ ><br>Stool color, Stool odor, pH of stool after Virechana Karma. <br/ ><br>BMI - Before and after treatment. <br/ ><br>Changes in signs and symptoms of NAFLD. <br/ ><br> <br/ ><br> <br/ ><br> <br/ ><br>Timepoint: Patients will be assessed after 15 days (After completion of Virechana Karma).

Secondary Outcome Measures

Name	Time	Method
Changes in signs and symptoms of NAFLD. <br/ ><br>USG of Abdomen-changes of fatty liver and/or cholestasis. <br/ ><br>Changes in Hepatic profile (SGOT, SGPT, Direct, Indirect & Total Bilirubin & Serum <br/ ><br>alkaline phosphatase) <br/ ><br>Changes in Lipid profile. <br/ ><br>Changes in Total Serum Bile Acids.Timepoint: Patients will be assessed before treatment, after 15 days <br/ ><br>and after 30 days of Shamana.