Metabolic Effects of Acute Cortisol Withdrawal in Adrenal Failure
Not Applicable
Completed
- Conditions
- Addison Syndrome
- Registration Number
- NCT00442390
- Lead Sponsor
- University of Aarhus
- Brief Summary
Effects of adrenal steroids is generelly drawn from studies of hypercortisolism. The effects of physiological cortisol substitution and withdrawal is studied and related to the clinical syndrome of adrenal insufficiency.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 10
Inclusion Criteria
- Female adrenal failure
- Age 18-50
- Written informed content
Exclusion Criteria
- Diabetes mellitus
- Cancer
- Thromboembolic events
- Pregnancy and lactation
- Heart disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method insulin sensitivity local protein turnover whole body protein turnover glucose metabolism serum metabolites serum hormone levels
- Secondary Outcome Measures
Name Time Method