Insulin Sensitivity and Substrate Metabolism in Patients With Cushing's Syndrome
Terminated
- Conditions
- Cushing's SyndromeInsulin Resistance
- Registration Number
- NCT00682084
- Lead Sponsor
- University of Aarhus
- Brief Summary
The purpose of this study is to investigate the effect og chronic elevated levels of cortisol on metabolism and insulin sensitivity.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 1
Inclusion Criteria
- Written consent
- Age between 18 and 70
- Diagnosed with Cushing's syndrome
Exclusion Criteria
- Suspected malignancy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Insulin sensitivity Before and after treatment
- Secondary Outcome Measures
Name Time Method Glucose tolerance, QoL, body composition, intrahepatic and intramyocellular fat, substrate metabolism. Before and after treatment
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link cortisol excess to insulin resistance in Cushing's Syndrome patients?
How does surgical treatment of Cushing's Syndrome compare to medical therapies in improving insulin sensitivity?
Which biomarkers correlate with metabolic improvements after cortisol normalization in Cushing's Syndrome?
What are the long-term adverse events of bilateral adrenalectomy for Cushing's Syndrome management?
How do glucocorticoid receptor antagonists complement surgical approaches in Cushing's Syndrome treatment?
Trial Locations
- Locations (1)
Department of Endocrinology
🇩🇰Aarhus C, Aarhus, Denmark
Department of Endocrinology🇩🇰Aarhus C, Aarhus, Denmark