Substrate Metabolism and Insulin Sensitivity in Patients With Hyperprolactinemia Before and After Treatment

Withdrawn

• Conditions: Insulin Resistance; Hyperprolactinemia
• Interventions: Other: Cabergoline

• Registration Number: NCT00699530
• Lead Sponsor: University of Aarhus

Brief Summary

The purpose of this study is to investigate the effects of chronic elevated levels of Prolactin on metabolism and insulin sensitivity by studying patients with hyperprolactinemia before and after treatment.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-05
• Study First Submitted: 2008-05-23
• Study First Submitted QC: 2008-06-13
• Study First Posted: 2008-06-18
• Status Verified: 2014-12
• Primary Completion: 2016-11
• Study Completion: 2016-11
• Last Update Submitted: 2017-12-21
• Last Update Posted: 2017-12-22

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Written consent
• Age between 18 and 70
• At diagnose a serum prolactin > 200 microgram/l (10 U/l)

Exclusion Criteria

• Hypothyroidism
• Use of any medication
• Pregnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Hyperprolactinemia	Cabergoline	Patients recently diagnosed with hyperprolactinemia

Primary Outcome Measures

Name	Time	Method
Insulin sensitivity	Before and after treatment

Secondary Outcome Measures

Name	Time	Method
QoL, body composition, intrahepatic and intramyocellular fat, substrate metabolism, glucose tolerance	Before and after treatment

Trial Locations

Locations (1)

Department of Endocrinology; 🇩🇰 Aarhus C, Aarhus, Denmark