Determination of intestinal microbiota in faecal specimens and intestinal mucosa biopsy specimens using bacterial DNA-based profiling methods.
Completed
- Conditions
- gut bacteria10017969obesitasintestinal microbiota
- Registration Number
- NL-OMON39196
- Lead Sponsor
- Vrije Universiteit Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 350
Inclusion Criteria
Age 18 years and older
Informed Consent
Elective colonoscopy
Patient living within a 15km radius from the VUmc
Pre-endoscopy colonic cleansing with Kleanprep®
Exclusion Criteria
Contraindication for colonoscopy
Contraindication for harvesting biopsy specimens
Other pre-endoscopy colonic cleansing than with Kleanprep®
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Primary outcome is a bacterial profile of the intestinal microbiota derived<br /><br>from the inter spacer region PCR (IS-PCR) technique. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Faecal and mucosal profiles will be compared together, and with other DNA based<br /><br>techniques. </p><br>