Sciatic Nerve Block for Ankle/Foot Surgeries. A Comparison Between a Premixed Solution of Lidocaine Plus Bupivacaine and Consecutive Infiltration of Lidocaine and Bupivacaine. A Double Blinded Randomised Controlled Prospective Study
Overview
- Phase
- Phase 4
- Intervention
- 2% lidocaine/adrenaline and 0.5% bupivacaine
- Conditions
- Open Reduction Internal Fixation(ORIF) of Lateral Malleolus
- Sponsor
- Cork University Hospital
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Postoperative analgesia/duration of block
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
Regional anaesthesia has become the cornerstone of multimodal analgesia. With the advent of ultrasound guided nerve blocks regional anaesthesia has achieved both greater efficacy and a better safety profile as the injection of local anaesthetic is performed under direct vision. This has allowed a reduction of the amount of local anaesthetic injected as compared to peripheral nerve stimulation technique . Blockade of sciatic nerve combined with saphenous nerve provides anaesthesia and analgesia for ankle/foot surgeries. Various combinations of local anaesthetics have been used to provide optimal blockade . A mixture of lidocaine with a long acting local anaesthetic is commonly used. This provides a rapid onset of blockade, but of a consistently shorter duration compared to a long acting local anaesthetic alone. We hypothesize that sequential perineural injection of lidocaine and bupivacaine provides similar onset but a longer duration of sensory block compared to the same dose and volume of local anaesthetic mixed in advance.
Investigators
DR. Jassim Rauf
Clinical Research/ Peripheral Nerve Blocks Fellow.
Cork University Hospital
Eligibility Criteria
Inclusion Criteria
- •Patients with ASA 1 - 3 status
- •scheduled to undergo semi-elective ankle/foot surgery under regional anaesthesia +/- sedation/opioid free general anaesthesia will be recruited
Exclusion Criteria
- •Patients having surgery on the medial aspect of the ankle/ foot
- •allergy to local anaesthetics
- •coagulopathy
- •malignancy or infection in the popliteal area
- •significant peripheral neuropathy
- •neurologic disorder of the lower extremity
- •any other contraindication to sciatic nerve block
- •pregnancy
- •history of alcohol or drug dependency/abuse (defined as \>40 IU/week)
- •a history of significant cognitive or psychiatric disorder that may affect patient assessment
Arms & Interventions
Premixed group
Patients will receive sciatic nerve block with premixed 7.5 mls of 2% lidocaine/adrenaline and 7.5 mls of 0.5% bupivacaine followed by an interval of 90 seconds with an injection of same amount of both drugs.
Intervention: 2% lidocaine/adrenaline and 0.5% bupivacaine
Sequential Group
Patients will receive a sciatic nerve block with 15 mls of 2% lidocaine/adrenaline followed by an interval of 90 seconds with 15 mls of 0.5% bupivacaine.
Intervention: 2% lidocaine/adrenaline and 0.5% bupivacaine
Outcomes
Primary Outcomes
Postoperative analgesia/duration of block
Time Frame: 24 hours
Secondary Outcomes
- onset of block(40 minutes)