Management of Polycystic Ovarian Syndrome
Phase 3
- Conditions
- Health Condition 1: E282- Polycystic ovarian syndrome
- Registration Number
- CTRI/2020/10/028282
- Lead Sponsor
- Central Council for Research in Homoeopathy
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Female aged 18 to 36 years
2.Oligomenorrhea/amenorrhea (two years after menarche)
3.Ultrasound findings of Polycystic ovaries
4.Clinical evidence of acne (acne global severity scale score 1 and above)
5.Written Informed consent from the patient
Exclusion Criteria
1. History of DM, Cushing disease, hyperprolactinemia, untreated hypo or hyperthyroidism, adrenal hyperplasia and adrenal tumor
2. Ovarian tumor, hyperthecosis and significant renal impairment
3. History of intake of drugs aldactone or metformin or history of OCP use or intake of drugs known to interfere with carbohydrate metabolism prior 4 weeks before enrolment.
4. Pregnancy, breast feeding
5. Cases with other systemic diseases or infections or on other treatment therapies
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Establishment of regular menstrual cycle along with either ultrasonological improvement of PCO or improvement in acneTimepoint: 6 months
- Secondary Outcome Measures
Name Time Method To compare the changes in domain scores of PCOSQ in both homoeopathic group and conventional treatment group at monthly interval for 6 months.Timepoint: 6 months;To compare the changes in insulin resistance through HOMA-IR in two groups.Timepoint: 6 months;To compare the changes in ultrasound reports of PCO at entry and 6 months in homoeopathy and conventional groups.Timepoint: 6 months;To compare the pregnancies achieved in cases of infertility in homoeopathy and conventional intervention groupsTimepoint: 6 months