The Validation of a CAD Screening Algorithm Based on Facial Photos in Community Population

Not yet recruiting

• Conditions: Coronary Artery Disease

• Registration Number: NCT06850233
• Lead Sponsor: China National Center for Cardiovascular Diseases

Brief Summary

The purpose of this study is to evaluate the effectiveness of a coronary heart disease screening algorithm based on facial photos in community population.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2025-02-21
• Study First Submitted QC: 2025-02-23
• Study First Posted: 2025-02-27
• Study Start: 2025-02-28
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-01
• Last Update Posted: 2025-03-04
• Primary Completion: 2025-12-31
• Study Completion: 2025-12-31

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Community population with a pre-test probability greater than 5% for coronary artery disease

Exclusion Criteria

• Prior percutaneous coronary intervention (PCI)
• Prior coronary artery bypass graft (CABG)
• The history of heart failure
• With artificially facial alteration (i.e. cosmetic surgery, facial trauma or make-up)
• Other situations which make patients fail to be photographed

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sensitivity of the algorithm	at the end of enrollment (6 months)	The sensitivity of the CAD screening algorithm assessed in the group
Specificity of the algorithm	at the end of enrollment (6 months)	The specificity of the CAD screening algorithm assessed in the group

Secondary Outcome Measures

Name	Time	Method
Discriminative capabilities	at the end of enrollment (6 months)	Area under receiver operating curve (AUC) of the algorithm assessed in the group
Positive predictive value (PPV)	at the end of enrollment (6 months)	PPV of the CAD screening algorithm assessed in the group
Negative predictive value (NPV)	at the end of enrollment (6 months)	NPV of the CAD screening algorithm assessed in the group
Diagnostic accuracy rate	at the end of enrollment (6 months)	Diagnostic accuracy rate of the algorithm assessed in the group

Trial Locations

Locations (1)

People's Road Community Health Service Center; 🇨🇳 Zhoukou, Henan, China