abour induction of patients with waters break and unfavorable cervix: oxytocin versus misoprostol

Phase 4

Recruiting

• Conditions: Premature Rupture of Fetal Membranes; C13.703.420.339

• Registration Number: RBR-39rmvb
• Lead Sponsor: Hospital de Clinicas de Porto Alegre

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-11-03
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Pregnant women admitted to the maternity of the Hospital de Clínicas de Porto Alegre (HCPA) with PROM; absence of labor; indication of labor induction; unfavorable cervix (Bishop index <4); between 34 and 41 weeks of gestation.

Exclusion Criteria

Multiple gestation; previous cesarean sections; previous transmural myomectomy; non-reassuring fetal status; more than 3 contractions in 10 minutes; placenta previa or vasa previa; umbilical cord prolapse; abnormal presentations (pelvic or transverse); active herpes infection; invasive carcinoma of the uterine cervix; having denied labor induction.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The aim of this study is demonstrate that the use of misoprostol to cervical ripening, in cases of RUPREME and unfavorable cervix, decreases the induction time until the beginning of the active phase of labor, increasing the chance of vaginal delivery.

Secondary Outcome Measures

Name	Time	Method
Secondary outcomes will be the mean time between the start of induction and delivery, side effects of both drugs and fetal outcomes.