Prehospital continuous positive airway pressure (CPAP) for acute cardiogenic pulmonary oedema: a randomised controlled trial.

Not Applicable

Suspended

• Conditions: Acute cardiogenic pulmonary oedema; Respiratory - Other respiratory disorders / diseases; Cardiovascular - Other cardiovascular diseases

• Registration Number: ACTRN12610000487011
• Lead Sponsor: Ambulance Research Institute, Ambulance Service of New South Wales

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-06-11
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Suspended
• Sex: All
• Target Recruitment: 660

Inclusion Criteria

i.aged greater than or equal to 18 years
ii.conscious (Glasgow Coma Scale (GCS)=15)
iii.presumed diagnosis of acute cardiogenic pulmonary oedema with:
a)increased work of breathing/accessory muscle use
b)hypoxic with oxygen saturation less than 92%
c)bilateral basal crackles on chest auscultation
d)respiratory rate greater than or equal to 28

Exclusion Criteria

i.inadequate ventilatory effort requiring ventilatory assistance (ie. hypoventilation requiring intermittent positive pressure ventilation (IPPV))
ii.systolic blood pressure less than 100 mmHg
iii.suspected acute myocardial infarction

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
In-hospital mortality. This will be assessed by a staff member of the research institute who will access the patient's hospital records. Ethical approval has been granted to access and source this information and reord it on a data colelction sheet.[From arrival in emergency department to a maximum in hospital follow up period of 30 days. Assessment of the outcome will occur within one week of this 30 day period concluding on a case by case basis.]