ON-SCENE Initiation of Extracorporeal CardioPulmonary Resuscitation During Refractory Out-of-Hospital Cardiac Arrest
- Conditions
- Cardiac ArrestECPR1001928010014623
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 390
- Age between 18 and 50 years
- Witnessed arrest (last seen well <5 min), OR signs of life (gasping, movement)
- Initial rhyme is VT/VF OR Suspected of having a pulmonary embolism
- Refractory cardiac arrest lasting longer than 20 minutes and shorter than 45
min
- CO2 et<1.2 kPa (10 mmHg) during CPR
- No clear echographic visualisation of either the femoral artery or the
femoral vein.
- Expected time from collapse to arrival at an ECPR center with a direct
available ECPR team is less than 30 min.
- Patients from a dispatch region which is not ready to deploy HEMS on a
routine basis for OHCA patients with the age between 18 and 50 years.
The following patients will be withdrawed after initial inclusion as soon as
the following information becomes available:
- Known malignancy
- Known intracranial haemorrhage/ischemia <6 weeks
- Care dependent for daily activities before arrest
- Patients with a *do not resuscitate* order, which was not known at time of
the arrest.
- Refusal of defferred consent by the next of kin or by the patient himself to
use the data.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Hospital survival and costs/QALY (EQ-D5), favourable neurological outcome (CPC<br /><br>1-2) at 6 and 12 months after cardiac arrest.</p><br>
- Secondary Outcome Measures
Name Time Method <p>To study the health care costs per OCHA patient (iPCQ, iMCQ), costs per Quality<br /><br>Adjusted Life Year (QALY), Quality of life 6 and 12 months after OHCA and total<br /><br>costs per life gained in the intervention group and in the control group</p><br>