Effect of aluminum chloride hexahydrate gel iontophoresis on hyperhidrosis
Phase 3
- Conditions
- Palmar hyperhidrosis.
- Registration Number
- IRCT20160506027762N2
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 32
Inclusion Criteria
Age 18-40, BMI 17-30.presence of focal, visible sweating for at least 6 months without any obvious cause, besides the presence of at least two of the following characteristics: Bilateral and relatively symmetrical sweating, frequency of at least one episode per week, impairment of daily activities of the patient, age of onset less than 25 years, a positive family history and cessation of focal sweating during sleep. HDSS 2 or 3 .
Exclusion Criteria
Having pacemaker or substantial metal implants located in electrical current path, being pregnant, suffering from systemic disease leading to hyperhidrosis and any central or peripheral nervous system diseases. SSR (sympathetic skin response) greater than normal or absent SSR
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sweating rate. Timepoint: before and 3 days, 1, 2, 3, 4, 8 weeks, and 24 weeks after the last treatment session. Method of measurement: Sweating rate with gravimetry test.;Quality of Life score in DLQI questionnaire. Timepoint: before and 3 days, 1, 2, 3, 4, 8 weeks, and 24 weeks after the last treatment session. Method of measurement: Quality of Life score with DLQI questionnaire.
- Secondary Outcome Measures
Name Time Method Sympathetic Skin Response (SSR). Timepoint: Before and after the application of one session iontophoresis. Method of measurement: Using a Medelec Synergy Electromyography instrument.