To determine whether changes in pulse wave velocity predict hypotension during dialysis

Not Applicable

Completed

• Conditions: Haemodialysis; Circulatory System

• Registration Number: ISRCTN12870218
• Lead Sponsor: Royal Free Hospital (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2013-11-01
• Last Update Posted: 20 February 2017

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. Patients with chronic kidney disease treated by haemodialysis
2. Patients who are able to provide valid consent
3. Patients who can have their blood pressure measured using an arm blood pressure cuff

Exclusion Criteria

1. Patients who do not fulfil the inclusion criteria
2. Patients who cannot provide valid informed consent
3. Patients who cannot have their blood pressure measured using an upper arm blood pressure cuff
4. Those with atrial fibrillation and other cardiac arrhythmias

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood pressure and pulse wave velocity are measured using a blood pressure cuff.<br>Blood pressure will be measured at the start of a dialysis session, then at 20 minutes, one hour and then hourly during the dialysis session. Changes in pulse wave velocity and heartbeat variation will be reviewed to determine whether these are related to changes in blood pressure during the dialysis session.

Secondary Outcome Measures

Name	Time	Method
Derived variables from pulse wave velocity.