To determine whether the change in blood pressure during head down position and transiently increasing breath volume can predict the response to fluid therapy in seriously ill patients on mechanical ventilator receiving low breath volume and in prone position during COVID pandemic
Not Applicable
- Conditions
- Health Condition 1: J80- Acute respiratory distress syndromeHealth Condition 2: B972- Coronavirus as the cause of diseases classified elsewhereHealth Condition 3: I959- Hypotension, unspecifiedHealth Condition 4: R098- Other specified symptoms and signsinvolving the circulatory and respiratory systemsHealth Condition 5: J189- Pneumonia, unspecified organismHealth Condition 6: J969- Respiratory failure, unspecified
- Registration Number
- CTRI/2021/06/034183
- Lead Sponsor
- atesh Prabu R
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Adult patients (Age > 18 yrs )
Acute circulatory failure
Receiving protective lung ventilation <= 6ml/kg IBW using Volume Assist Control mode, without any spontaneous activity
Need of prone ventilation as decided by treating physician.
Exclusion Criteria
Cardiac arrhythmias, Acute myocardial infarction
Previously known significant valvular disease or intracardiac shunt
Air leakage through chest drains
Right heart failure
An urgently required fluid challenge.
Abdominal compartment syndrome, and pregnancy
Raised intracranial hypertension
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method