JPRN-jRCTs042180119已完成2 期
A feasibility study of intensity modulated radiotherapy with chemotherapy for locally advanced non-small-cell lung cancer
Harada Hideyuki0 个研究点目标入组 22 人开始时间: 2019年3月19日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 22
研究概览
简要总结
The primary endpoint for tolerability of chemoradiotherapy with intensity-modulated radiotherapy could not be achieved. However, intensity-modulated radiotherapy could be completed in all but one case, demonstrating good survival and safety.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 < 75age old（—）
- 性别
- All
入选标准
- •1)Non-small cell lung cancer(NSCLC) diagnosed by cytological or histological examination
- •2)Inoperable
- •3)Clinical stage 3 NSCLC, possible for definitive radiotherapy
- •4)No previous chemotherapy or radiotherapy
- •5)Measurable lesions
- •6)Age; 20 -75 years old
- •7)ECOG performance status:0-1
- •8)Ingestible
- •9)Sufficient function in bone marrow, heart, lung, liver and kidney
- •10)Written informed consent
排除标准
- •1)Active double cancer
- •2)Severe infection or morbidity
- •3)HBs antigen positive
- •4)Previous thoracic radiotherapy
- •5)Interstitial pneumonia or fibrosis on CT
- •6)Severe emphysema or chronic bronchitis or asthma
- •7)Severe drug allergy
- •8)Severe diabetes
- •9)Unstable angina or myocardial infarction within 6 months
- •10)Febrile more than or equal to 38 degree
- •11)Systemic use of corticosteroid or immunosuppressive drug
- •12)Expectant mother or breast feeding woman or not agreed with contraception
- •13)Psychiatric disorder
- •14)Unsuitable for enrollment judged by attending physician
研究者
相似试验
已完成
不适用
Accelerated Intensity Modulated Radiation Therapy (AIMRT) to the Breast After Segmental MastectomyBreast CancerNCT02606708NYU Langone Health314
已完成
1 期
Radical Pleurectomy/Decortication (PD) and Intensity Modulated Radiotherapy (IMRT)MesotheliomaLung CancerNCT01134146M.D. Anderson Cancer Center11
Unknown
2 期
A Phase II Study of Postoperative S-1-Based Chemoradiotherapy in Gastric CancerStomach NeoplasmsChemoradiotherapy, AdjuvantRadiotherapy, Intensity-ModulatedNCT02296658Chinese Academy of Medical Sciences60
已完成
不适用
Intensity Modulated Radiotherapy in Recurrent T1-2 Nasopharyngeal CarcinomaNasopharyngeal Cancer RecurrentNCT02113423Fujian Cancer Hospital168
已完成
不适用
Feasibility of IMRT Modulation to Account for Scattered Radiation From Dental Fillings in Head and Neck CancerHead and Neck CancerNCT01576939Stanford University30