Effects of High Frequency Repetitive Transcranial Magnetic Stimulation Combined Motor Learning on Motor Function and Grip Force for Upper Limbs and Activities of Daily Living in Sub-acute Stroke Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Stroke, Acute
- Sponsor
- Chungnam National University Sejong Hospital
- Enrollment
- 30
- Primary Endpoint
- Fugl Meyer Assessment - Upper Limb(FMA-U/L)
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
This study is to present the effect of a program combining high frequency repetitive transcranial magnetic stimulation with motor learning on upper limb motor function and grip strength and activities of daily motion in patients with subacute stroke.
Purpose : This study was to investigate the effects of high frequency repetitive transcranial magnetic stimulation combined with motor learning effects motor function and grip force for upper limbs and activities of daily living of subacute stroke patients.
Subjects : Thirty individuals with subacute stroke, satisfying the selection criteria, were selected for this study. Subject were randomly allocated into 14 high frequency repetitive transcarnial magnetic stimulation+motor learning group(experimental group), 16 sham repetitive transcranial magnetic stimulation+motor learning group(control group).
Intervention : 12 sessions, 3d/wk, 4week Studies : upper limb functional assessment(FMA-U/L, BBT), hand grip force assessment(disital hand dynamometer), activities daily of living assessment(K-MBI) Evaluation : 1)pre test 2)post test
Investigators
JungWoo Shim
Principal Investigator
Chungnam National University Sejong Hospital
Eligibility Criteria
Inclusion Criteria
- •Hemiplegia from stroke
- •Factors within six months of onset
- •Found to have subcortex damage through diagnoses of magnetic resonance imaging(MRI)
- •Had motor defects on the damaged upper extremities
- •Korean version Mini mental state examination(MMSE-K) score greater than 24 points
Exclusion Criteria
- •Permanent damage such as heart vein
- •Upper limb fractures
- •Neurological damage such as Parkinson's, multiple sclerosis
- •Other reasons limiting upper limb movement
- •Epilepsy or family history of epilepsy
- •wearing a metal tube in skull or pacemaker
- •The lesion at occipital lobe
Outcomes
Primary Outcomes
Fugl Meyer Assessment - Upper Limb(FMA-U/L)
Time Frame: Change from baseline at the end of four weeks intervention
The FMA-U/L score is a tool for evaluating the body's structure, function, and activity level as an evaluation tool for evaluating motor function according to Brunnstrom's recovery phase of Step 6. The minimum value is 0 point and the maximum value is 66 points, and the higher the score, the better the outcome.
Secondary Outcomes
- Box and Block Test(BBT)(Change from baseline at the end of four weeks intervention)
- Digital hand dynamometer(Change from baseline at the end of four weeks intervention)
- Korean version of the Modified Barthel Index(K-MBI)(Change from baseline at the end of four weeks intervention)