Supplement Intake in Infertile Men;the Effect on Sperm Parameters,Fertilization Rate and Embryo Quality

Not Applicable

• Conditions: Oligospermia
• Interventions: Dietary Supplement: Vitamale

• Registration Number: NCT01520584
• Lead Sponsor: Hillel Yaffe Medical Center

Brief Summary

The vitamin,minerals and amino acid supplementation for 3 months will improve the semen parameters,fertilization rate and embryo quality in subfertile men undergoing IVF treatment

Detailed Description

With the supplement intake containing amino acids, vitamins and minerals designed to improve sperm parameters, the couples undergoing IVF treatment will benefit as the change and improvement of sperm parameters will increase the fertilization rate and improve the embryo quality thus allowing shorter time for pregnancy achievement and less frustration with long duration of treatments

Study Timeline

• Status Verified: 2012-01
• Study Start: 2012-01
• Study First Submitted: 2012-01-14
• Study First Submitted QC: 2012-01-25
• Last Update Submitted: 2012-01-25
• Study First Posted: 2012-01-30
• Last Update Posted: 2012-01-30
• Primary Completion: 2014-01
• Study Completion: 2016-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Male
• Target Recruitment: 40

Inclusion Criteria

• healthy male age 20-50
• at least one IVF cycle without pregnancy
• sperm parameters:
• Oligospermia 5-20*106
• Teratospermia 6-14% normal forms
• Asthenospermia <30% motility

Exclusion Criteria

• female factor infertility
• age > 50 or under 20
• testicular problem on physical examination
• history of malignancy and /or chemotherapy
• usage of antiandrogen/testosterone
• history of drug abuse/alcohol
• a known endocrinological problem
• current STD or genitourinary infection
• Retrograde Ejaculation
• Y chromosome microdeletion
• Karyotype abnormalities

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
vitamale	Vitamale	-
sham pill	Vitamale	-

Primary Outcome Measures

Name	Time	Method
Sperm parameters	3 months of treatment	Men suffering from a "male factor" problem and after one failed IVF treatment will be given the supplement for 3 months after which the sperm parametrs will be evaluated and compared to pre-supplement data and later the embryo quality and fertilization rate will reviewed analyzed and compared

Trial Locations

Locations (1)

Hillel Yaffe Medical Center; 🇮🇱 Hadera, Israel