Validity and feasibility of accelerometers for assessing habitual physical activity in children with mitochondrial disease.

Completed

Conditions: Mitochondrial disorders
10021605

Registration Number: NL-OMON43036

Lead Sponsor: Radboud Universitair Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 25

Inclusion Criteria

Healthy children:
o Healthy children aged 4-16 years old;Children with a mitochondrial disorder:
o Genetic mutation leading to a mitochondrial disorder
o Being capable of following instructions

Exclusion Criteria

Healthy children:
o Having a known health condition that could affect the physical activity, such as Attention Deficit Hyperactivity Disorder (ADHD), for which he/she visited the general practitioner or a paediatrician.
o Visited the general practitioner or a paediatrician for tiredness in the past year;Children with a mitochondrial disorder:
o The study is estimated to be too burdensome to the patient
o Daily use of a wheelchair

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Study i)<br /><br>The feasibility of the accelerometers during the movement-protocol in lab-gym<br /><br>situation, and the validity of the different parameters calculated by the<br /><br>software of the accelerometers compared to visual observations (video).<br /><br><br /><br>Study ii)<br /><br>The validity, feasibility and test-retest reliability of the selected<br /><br>accelerometer in measuring habitual physical activity of children with a<br /><br>mitochondrial disorder during a longer period in the home situation</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The different parameters calculated by the software of the selected<br /><br>accelerometer, i.e.:<br /><br>o Activity counts (counts/minute)<br /><br>o Physical activity intensity (% sedentary, % light, % moderate, % vigorous)<br /><br>o Steps taken (n)<br /><br>o Body position (% laying, % sitting, % standing, % walking)<br /><br>o Energy expenditure (MET-rates, kcal)<br /><br>o Sleep-parameters (total sleep time, sleep efficiency, sleep onset latency and<br /><br>wake after sleep onset)</p><br>