Intravenous butorphanol versus intravenous tramadol in patients operated for breast cancer- a randomized control trial

Tata memorial hospital0 个研究点目标入组 90 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•1)Age greater than 18 years and less than 65 years.
•2)ASA status I and II
•3)Elective unilateral breast surgeries [simple mastectomy with axillary clearance (SMAC),Modified radical mastectomy (MRM), breast conserving therapy (BCT) and oncoplasty]

•1. Patients taking opioids on a regular basis/ opioid abuser.
•2. Patients allergic to any of the following drugs- tramadol, butorphanol, paracetamol, diclofenac.
•3. Patients on anti-epileptics, anti-depressants, anti-psychotics, and warfarin.
•4. Patient complaining of nausea/vomiting prior to surgery. (PONV score 1 or more)
•5. History of motion sickness/ vertigo/ Inner ear disease
•6. BMI > 30 or Weight < 45kgs
•7. Patient or patientâ??s relatives unable to understand the language employed for counselling
•8. Non-consenting patient.
•9. pregnant/nursing mothers.
•Immediate post-operative exclusion criteria
•a)Patients having severe pain [numerical rating scale (NRS) >7] in the immediate post-operative period in recovery room (RR) and requiring immediate dose of fentanyl and patients having no pain[numerical rating scale - 0].
•b)Patients with vomiting post extubation or in the recovery before administration of the study drug.
•c)Intra operative complications which might warrant the patient to remain intubated in the immediate post-operative period.

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