Evaluation of the effect of Topcial Glyceryl Trinitrate on radial artery diameter for catheterisation in newborns: a randomised controlled trial

Phase 1

Recruiting

• Conditions: arterial cannulation; critical care; neonatal intensive care unit; Emergency medicine - Other emergency care

• Registration Number: ACTRN12623000509662
• Lead Sponsor: Perth Children's Hospital(Child And Adolescent Health Service)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-05-17
• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1.Neonates >34 weeks of gestation admitted to Neonatal Intensive Care Unit (NICU) needing peripheral arterial line for sampling or invasive blood pressure monitoring.
2.Neonates >34 weeks of gestation admitted to NICU scheduled for elective surgery- general surgery needing peripheral arterial cannulation for hemodynamic monitoring or frequent blood sampling (Peri-operative).

Exclusion Criteria

1.Neonates with previous attempts at radial arterial cannulation, hematomas at cannulation site, abnormal Allen’s test, hypercoagulable state, coagulopathy, and peripheral vascular disease.
2.Neonates with unstable vital signs including hypotension, shock or significant arrythmias.
3.Neonates undergoing cardiac surgery
4.Neonates with increased intracranial pressure, intracranial haemorrhage, and recent use of Sildenafil.
5.Neonates with visible deformity in the radial artery area.

Study & Design

• Study Type: Interventional
• Study Design: Not specified