Yizhi Baduanjin for Patients With Cognitive Impairment
- Conditions
- Mild Cognitive Impairment (MCI)
- Interventions
- Other: Yizhi Baduanjin (Eight Pieces of Brocades for Mental Health Promotion)
- Registration Number
- NCT06453941
- Lead Sponsor
- The University of Hong Kong
- Brief Summary
The trial is designed to examine whether Yizhi Baduanjin could slow down and improve in memory, logical thinking and cerebral function in patients with mild cognitive impairment (MCI). 30 MCI patients will be recruited and randomly assigned to Yizhi Baduanjin intervention group control group for 6 months. The primary outcome is changes in Montreal Cognitive Assessment (MoCA) questionnaire; other outcome includes Cognitive Function Assessment questionnaire.
- Detailed Description
Alzehimer Disease (AD), generally known as dementia, is system of pathological changes of the central nervous system, with the major symptoms of progressive memory loss, cognitive disorder, personality changes and difficulty speaking. Mild Cognitive Impairment (MCI) is always regarded as "prodromal AD", and as a stage of AD in the revised diagnostic guidelines. It is a condition with minor memory decline, and minor difficulties with attention and learning. MCI patients have a much higher risk of progress to AD than the general population. AD increases along with aging, while aging is a worsening global issue. The onset of AD is difficult to recognize, and the progression is non-reversible and without cure, while the intervention during the MCI stage would be effective for preventing the progression to AD. The pathogenesis of MCI is yet to be investigated, so the pharmaceuticals are under debate. The non-drug therapies have few side effects and are more acceptable to patients, The investigators believe that Yizhi Baduajin, a newly complied routine based on the traditional Chinese medical health practice Baduanjin, is a possible intervention to prevent MCI and AD which could be practiced for long-term. Therefore, this pilot controlled trial is proposed to verify the effect of Yizhi Baduanjin and investigate how it improve and promotes mental and cerebral functions, and to explore and develop a replicable model of Yizhi Baduanjin MCI service package that includes MCI screening and education, as well as the Yizhi Baduanjin teaching.
The hypothesis is that the progression of MCI patients who practice Yizhi Baduanjin will slow down and improve in memory, logical thinking and cerebral function than MCI patients who do not practice. Also, Yizhi Baduanjin is a more acceptable intervention for middle-aged and elderly people, it is also easier to popularize in replicable model at a lower cost.
The trial will recruit 30 participants, and divide randomly into two groups with 15 participants each. The experimental group will practice Yizhi Baduanjin as an intervention for 6 months, and the participants will be examined for assessment indicators on the 1st, 3rd, 6th month after the intervention starts. The control group has no intervention until 6 months after the intervention of the experimental group started, but the participants will be examined for the same assessment indicators together with the experimental group. The Montreal Cognitive Assessment (MoCA) questionnaire and Cognitive Function Assessment questionnaire will be used as the assessment instruments, and data collected from the two groups will be compared and assessed.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 30
- 60 to 75 years old.
- Voluntarily and sign the informed consent form.
- Non-handicapped, able to complete the cognitive function examination.
- Fulfill the diagnostic criteria.
- Montreal Cognitive Assessment (MoCA )Scale < 26
- Fail to meet the inclusion criteria.
- Fail to comply to the requirements, or fail to complete the examination.
- Unwilling or unable to learn and practice the Yizhi Baduanjin routine.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Yizhi Baduanjin group Yizhi Baduanjin (Eight Pieces of Brocades for Mental Health Promotion) The Yizhi Baduanjin group will practice Yizhi Baduanjin as intervention for 6 months, and the participants will be examined for assessment indicators on the 1st, 3rd, 6th month after the intervention started.
- Primary Outcome Measures
Name Time Method Changes in Montreal Cognitive Assessment (MoCA ) Baseline, 1-month, 3-month, 6-month Questionnaire with 8 categories, 33 items with a total score of 30.
- Secondary Outcome Measures
Name Time Method Changes in Cognitive Function Assessment Baseline, 1-month, 3-month, 6-month Questionnaire with 4 Categories, total items and scores vary according to participants' response.
Trial Locations
- Locations (1)
The University of Hong Kong
ðŸ‡ðŸ‡°Hong Kong, Hong Kong