Predicting Favorable Outcomes in Hospitalized Covid-19 Patients

Completed

• Conditions: COVID; Corona Virus Infection; Adverse Event
• Interventions: Other: EPIC risk score display

• Registration Number: NCT04570488
• Lead Sponsor: NYU Langone Health

Brief Summary

Testing use of predictive analytics to predict which COVID-19+ patients are at low risk for an adverse event (ICU transfer, intubation, mortality, hospice discharge, re-presentation to the ED, oxygen requirements exceeding nasal cannula at 6L/Min) in the next 96 hours

Detailed Description

To assess if display of low risk of adverse event in EPIC can safely reduce length of stay and plan for discharge.

Study Timeline

• Study Start: 2020-05-15
• Study First Submitted: 2020-09-25
• Study First Submitted QC: 2020-09-29
• Study First Posted: 2020-09-30
• Primary Completion: 2021-12-07
• Study Completion: 2021-12-07
• Status Verified: 2022-12
• Last Update Submitted: 2022-12-22
• Last Update Posted: 2022-12-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1415

Inclusion Criteria

Adult hospitalized COVID19+ patients predicted to have no adverse event at 96 events with a threshold at 90% PPV, with at least one low risk during their admission who are discharged alive and have not been in the ICU

Exclusion Criteria

Age < 18 years not hospitalized for COVID19+.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Quality improvement - Display	EPIC risk score display	Display of risk score/ colored flag in Epic patient list column; will be viewable to all frontline workers

Primary Outcome Measures

Name	Time	Method
Reduction in days from first low-risk score to discharge	96 Hours	Reduction in days from first low-risk score to discharge

Secondary Outcome Measures

Name	Time	Method
Reduction in length of stay (LOS)	96 hours	Reduction in LOS for green patients that have not been in the ICU
Reduction in GTD vs. LOS	96 hours	Reduction in GTD vs. LOS for all green patients discharged alive vs all patients discharged alive
No change in 30 day re-ED presentation or hospital admission rate for cohort	96 hours	No change in 30 day re-ED presentation or hospital admission rate for cohort

Trial Locations

Locations (1)

NYU Langone Health; 🇺🇸 New York, New York, United States