A prospective cohort study in the development of type 2 diabetes and cardiovascular disease: The CODAM study
- Conditions
- diabetes and cardiovascular disease100192801001265310018424
- Registration Number
- NL-OMON37934
- Lead Sponsor
- niversiteit Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 500
Inclusion Criteria
Partricipant in baseline measurement of the CODAM study (MEC99-112)
Exclusion Criteria
None, except for limitations that interfere with any of the procedured to obtain informed consent according to the Helsinki declaration
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>(1) Development and progression of insulin resistance, glucose intolerance and<br /><br>type 2 diabetes in the CODAM study population.<br /><br>(2) Development and progression of atherosclerosis, vascular dysfunction and<br /><br>CVD in the CODAM study population.<br /><br><br /><br>Specific outcomes:<br /><br>- International Classification of Diseases version 10 (ICD-10 codes) :<br /><br>E11 (type 2 diabetes)<br /><br>I10-15 (hypertensive disease)<br /><br>I20-25 (ischaemic heart disease)<br /><br>- Subcutaneous and visceral fat<br /><br>- Ectopic fat in the liver<br /><br>- insulin resistance and glucose tolreance status<br /><br>- Measures of arterial structure (including carotid Intima-Media-Thikcness &<br /><br>Ankle-Brachial Index) and function (including arterial stiffness)<br /><br>- Presence of Metabolic Syndrome (according to the most recent defintion of<br /><br>Alberti et al (2009)) </p><br>
- Secondary Outcome Measures
Name Time Method