Examine the Effect of Repetitive Transcranial Magnetic Stimulation (rTMS) Over the Symptoms of Autism Spectrum Disorder
Trial Snapshot
- Phase
- Phase 1
- Sponsor
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- continuous performance test
Study Overview
Brief Summary
rTMS over dorsolateral prefrontal cortex is effective in reducing repetitive behaviors in adults with autistic spectrum disorder rTMS over posterior superior temporal sulcus is effective in improving social ability in adults with autistic spectrum disorder
Detailed Description
First, we will apply one session intermittent theta burst stimulation over dorsolateral prefrontal cortex, posterior superior temporal sulcus and inion as control with one week interval in adults with autism spectrum disorder. Second, we will apply 5 sessions intermittent theta burst stimulation within one week over dorsolateral prefrontal cortex or posterior temporal sulcus depending on the results of our first phases.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 40 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •adults with autistic spectrum disorder
Exclusion Criteria
- •schizophrenia
- •bipolar affective disorder
- •major depressive disorder
- •any systemic disease especially epilepsy
Outcomes
Primary Outcomes
continuous performance test
Time Frame: continuous performance test will be arranged before and after rTMS within one hour
continuous performance test will be arranged before and after rTMS within one hour
Secondary Outcomes
- Yale-Brown Obsessive Compulsive Scale(Yale-Brown Obsessive Compulsive Scale will be evaluated before and after rTMS within one week)