NCT01687452已完成不适用
Microparticles, Vector of Genetic Information During HIV Infection ?
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- NUMBER OF miRNAs
研究概览
简要总结
The aim of the investigators study is to demonstrate in healthy subjects and a cohort of patients infected with HIV, the presence of miRNAs in circulating peripheral blood microparticles (MPs).
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 50 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Age of 40 +/-10 years
- •Seronegativity for the HIV 2
- •Patients of the group A: seropositivity for the HIV 1 confirmed in ELISA and Western Blot for at least 2 years and having never received from antiretroviral treatment, with a viral plasmatique load > 1000 copies / ml
- •Patients of the group B: seropositivity for the HIV 1 confirmed in ELISA and Western Blot for at least 2 years and under stable antiretroviral treatment for at least 6 months, with a viral load undetectable plasmatique (< 40 copies / ml)
- •patients of the group C : Matching on the age (+/-3 years) to a patient
- •Be considered healthy by the Investigator after a clinical examination Seronegativity for the HIV 1 confirmed in ELISA the day of the taking
排除标准
- •group A et B
- •Age of < 30 years and > in 50 years
- •Seropositivity for the HIV 2
- •group C Seropositivity for the HIV 2
- •Be under medicinal treatment
结局指标
主要结局
NUMBER OF miRNAs
时间窗: 2 YEARS
次要结局
- Demonstrate the presence of miRNAs in microparticles(2 YEARS)
研究者
研究点 (2)
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