Microparticles, Vector of Genetic Information During HIV Infection
Not Applicable
Completed
- Conditions
- HIV,
- Registration Number
- NCT01687452
- Lead Sponsor
- Assistance Publique Hopitaux De Marseille
- Brief Summary
The aim of the investigators study is to demonstrate in healthy subjects and a cohort of patients infected with HIV, the presence of miRNAs in circulating peripheral blood microparticles (MPs).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 15
Inclusion Criteria
- Age of 40 +/-10 years
- Seronegativity for the HIV 2
- Patients of the group A: seropositivity for the HIV 1 confirmed in ELISA and Western Blot for at least 2 years and having never received from antiretroviral treatment, with a viral plasmatique load > 1000 copies / ml
- Patients of the group B: seropositivity for the HIV 1 confirmed in ELISA and Western Blot for at least 2 years and under stable antiretroviral treatment for at least 6 months, with a viral load undetectable plasmatique (< 40 copies / ml)
- patients of the group C : Matching on the age (+/-3 years) to a patient
- Be considered healthy by the Investigator after a clinical examination Seronegativity for the HIV 1 confirmed in ELISA the day of the taking
Exclusion Criteria
group A et B
- Age of < 30 years and > in 50 years
- Seropositivity for the HIV 2
group C Seropositivity for the HIV 2
- Be under medicinal treatment
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method NUMBER OF miRNAs 2 YEARS
- Secondary Outcome Measures
Name Time Method Demonstrate the presence of miRNAs in microparticles 2 YEARS
Trial Locations
- Locations (1)
Assistance Publique Hopitaux de Marseille
🇫🇷Marseille, France
Assistance Publique Hopitaux de Marseille🇫🇷Marseille, France