Effect of lung protective ventilation on oxygenation , ventilatory parameters and inta-cranial pressure.
Not Applicable
- Conditions
- Health Condition 1: C15-C26- Malignant neoplasms of digestive organs
- Registration Number
- CTRI/2020/10/028465
- Lead Sponsor
- I
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. ASA physical status i-iii
2. Age group of 18-70
3.BMI < 30
4. Candidates posted for upper abdominal surgeries and surgical duration expected to exceed beyond 2 hours
Exclusion Criteria
1.Mechanical ventilation of > 1 hour within the last 2 weeks before surgery
2. Body mass index � 35 kg/m2
3. Acute respiratory failure (pneumonia, acute lung injury or acute respiratory distress syndrome)
- Emergency surgery
- Sepsis or septic shock
- Progressive neuromuscular illness
- Intra-thoracic surgery
- Pregnancy
- Orbital tumors
- Optic neuritis
- Glaucoma
- Refusal to participate
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Effect of periodic recruitment manuever on PaO2, P:F, driving pressure, respiratory compliance <br/ ><br>Effect of periodic recruitment manuever on ONSDTimepoint: Periodic recruitent manuever will be done to.set optimum PEEP at 30, 60, 120 th minutes after induction of general anesthesia
- Secondary Outcome Measures
Name Time Method ot applicableTimepoint: Not applicable