Gastric Emptying measured with MRI and Scintigraphy in patients with successful versus unsuccessful weight loss after Sleeve gastrectomy

Recruiting

Conditions: Bariatrische chirurgie
maagontlediging
obesitas
Bariatisc surgery
obesity

Registration Number: NL-OMON49419

Lead Sponsor: Rijnstate Ziekenhuis

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 24

Inclusion Criteria

- Women aged between 20 and 55 years who underwent sleeve gastrectomy as
primary procedure with either TWL < 25% or TWL > 35%.
- Patients who had a follow-up period of 2-3 years after sleeve gastrectomy

Exclusion Criteria

- Maximum BMI >50 kg/m2
- Patients with a disease known to affect appetite, gastric emptying or
gastrointestinal motility
- Patients who are unable to stop medications that affect gastric emptying
and/or motility prior to measurements. It is depending on t1/2 for how long
they need to stop medication.
- Patients who started menopause
- Patients with gastrointestinal problems or, gastric or intestinal diseases
- Patients with a drug or alcohol addiction
- Patients who are unable to stop smoking for 24 hours
- Patients who are pregnant or lactating
- Patients who have an intolerance or allergy for one of the components of the
test product
- Patients who have a contra-indication to MRI scanning

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary objectives:<br /><br>1. To compare gastric emptying rate between patients with successful and<br /><br>unsuccessful weight loss two years after sleeve gastrectomy.<br /><br>2. To compare gastric emptying rate as measured with MRI to gastric emptying<br /><br>rate measured with scintigraphy</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary objectives:<br /><br>1. To compare sleeve characteristics between patients with successful and<br /><br>unsuccessful weight loss<br /><br>2. Assess the association between gastric emptying rate and gastric sleeve<br /><br>characteristics in each group.<br /><br>3. To compare subjective ratings of gastric fullness and wellbeing between<br /><br>patients with successful and unsuccessful weight loss. </p><br>